2. Metabolic Disease

Metabolic Disease

Metabolic Disease

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Metabolic diseases is defined by a constellation of interconnected physiological, biochemical, clinical, and metabolic factors that directly increases the risk of cardiovascular disease, type 2 diabetes mellitus, and all cause mortality. Associated conditions include hyperuricemia, fatty liver (especially in concurrent obesity) progressing to nonalcoholic fatty liver disease, polycystic ovarian syndrome (in women), erectile dysfunction (in men), and acanthosis nigricans. Metabolic disease modeling is an essential component of biomedical research and a mandatory prerequisite for the treatment of human disease. Somatic genome editing using CRISPR/Cas9 might be used to establish novel metabolic disease models.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-W004066S
    Ac-Ala-OH-d3 1485548-36-4 ≥99.0%
    Ac-Ala-OH-d3 is the deuterium labeled Ac-Ala-OH. Ac-Ala-OH is an endogenous metabolite.
    Ac-Ala-OH-d3
  • HY-W004263S
    1-Eicosanol-d41 349553-89-5 98%
    1-Eicosanol-d41 (Arachidyl alcohol-d41) is the deuterium labeled 1-Eicosanol (HY-W004263). 1-Eicosanol is a natural compound with antioxidant activity found in Justicia insularis leaves. 1-Eicosanol can be used as an antioxidant.
    1-Eicosanol-d41
  • HY-W004305R
    Hexadecanal (Standard) 629-80-1
    Hexadecanal (Standard) is an analytical standard for Hexadecanal. This product is intended for research and analytical applications. Hexadecanal (Palmitaldehyde), a volatile, long-chain fatty aldehyde, is released from human feces, skin, and breath. The hexadecanal receptor (OR37B) is highly conserved in mammals. Hexadecanal may exert its effects by modulating functional connectivity between social evaluation brain substrates and aggression execution brain substrates. Hexadecanal has also been shown to have a strong deterrent effect on black ants. Hexadecanal has potential for use in startle response and aggression behavior
    Hexadecanal (Standard)
  • HY-W006371R
    (2-Aminoethyl)phosphonic acid (Standard) 2041-14-7
    (2-Aminoethyl)phosphonic acid (Standard) is the analytical standard of (2-Aminoethyl)phosphonic acid (HY-W006371). This product is intended for research and analytical applications. (2-Aminoethyl)phosphonic acid is an endogenous metabolite and amino acid analog. (2-Aminoethyl)phosphonic acid can be used for the synthesis of biological macromolecules and the preparation of hydrogels.
    (2-Aminoethyl)phosphonic acid (Standard)
  • HY-W007346R
    m-Anisaldehyde (Standard) 591-31-1
    m-Anisaldehyde (Standard) is the analytical standard of m-Anisaldehyde. This product is intended for research and analytical applications. m-Anisaldehyde is an endogenous metabolite.
    m-Anisaldehyde (Standard)
  • HY-W007346S
    m-Anisaldehyde-d3 1219795-07-9 98%
    m-Anisaldehyde-d3 is the deuterium labeled m-Anisaldehyde. m-Anisaldehyde is an endogenous metabolite.
    m-Anisaldehyde-d3
  • HY-W007539R
    2,4-Dihydroxybenzaldehyde (Standard) 95-01-2
    2,4-Dihydroxybenzaldehyde (Standard) is the analytical standard of 2,4-Dihydroxybenzaldehyde. This product is intended for research and analytical applications. 2,4-Dihydroxybenzaldehyde is an endogenous metabolite.
    2,4-Dihydroxybenzaldehyde (Standard)
  • HY-W007686R
    Imidazoleacetic acid hydrochloride (Standard) 3251-69-2
    Imidazoleacetic acid (hydrochloride) (Standard) is the analytical standard of Imidazoleacetic acid (hydrochloride). This product is intended for research and analytical applications. Imidazoleacetic acid hydrochloride is a γ-aminobutyric acid receptor agonist. Imidazoleacetic acid hydrochloride inhibits GABA-T in a non-competitive manner, with a Ki value of 0.34 mM. Imidazoleacetic acid hydrochloride increases total free GABA in brain[1][2][3].
    Imidazoleacetic acid hydrochloride (Standard)
  • HY-W007888R
    2-Hydroxy-4-methylbenzaldehyde (Standard) 698-27-1
    Prostaglandin E1 (Standard) is the analytical standard of Prostaglandin E1. This product is intended for research and analytical applications. Prostaglandin E1 (Alprostadil) is a prostanoid receptor ligand, with Kis of 1.1 nM, 2.1 nM, 10 nM, 33 nM and 36 nM for mouse EP3, EP4, EP2, IP and EP1, respectively. Prostaglandin E1 induces vasodilation and inhibits platelet aggregation. Prostaglandin E1 can be used as a vasodilator for the research of peripheral vascular diseases.
    2-Hydroxy-4-methylbenzaldehyde (Standard)
  • HY-W008097R
    3,3-Dimethylglutaric acid (Standard) 4839-46-7
    3,3-Dimethylglutaric acid (Standard) is the analytical standard of 3,3-Dimethylglutaric acid. This product is intended for research and analytical applications. 3,3-Dimethylglutaric acid, a member of methyl-branched fatty acids, is a endogenous metabolite occasionally found in human urine[1].
    3,3-Dimethylglutaric acid (Standard)
  • HY-W008226R
    Phloracetophenone (Standard) 480-66-0
    Oxprenolol (hydrochloride) (Standard) is the analytical standard of Oxprenolol (hydrochloride). This product is intended for research and analytical applications. Oxprenolol hydrochloride (Ba 39089) is an orally bioavailable β-adrenergic receptor (β-AR) antagonist with a Ki of 7.10 nM in a radioligand binding assay using rat heart muscle.
    Phloracetophenone (Standard)
  • HY-W008270R
    2(5H)-Furanone (Standard) 497-23-4
    2(5H)-Furanone (Standard) is the analytical standard of 2(5H)-Furanone. This product is intended for research and analytical applications. 2(5H)-Furanone is an endogenous metabolite.
    2(5H)-Furanone (Standard)
  • HY-W008452S
    H-Tyr(3-I)-OH-13C6 2483735-06-2 98%
    H-Tyr(3-I)-OH-13C6 is the 13C-labeled H-Tyr(3-I)-OH. H-Tyr(3-I)-OH is a potent and effective tyrosine hydroxylase inhibitor. H-Tyr(3-I)-OH is an intermediate in the production of thyroid hormones and has a role as a human or mouse metabolite.
    H-Tyr(3-I)-OH-13C6
  • HY-W008613A
    Amitriptyline pamoate 17086-03-2 98%
    Amitriptyline pamoate is a common oral anticholinergic. Amitriptyline pamoate has anticholinergic properties. Amitriptyline pamoate can be used to quantify anticholinergic adverse reactions in patients taking amitriptyline and placebo .
    Amitriptyline pamoate
  • HY-W008614R
    Lansoprazole sulfone (Standard) 131926-99-3
    Lansoprazole sulfone (Standard) is the analytical standard of Lansoprazole sulfone. This product is intended for research and analytical applications. Lansoprazole sulfone (AG-1813) is an orally active and selective inhibitor of H+, K+-ATPase. Lansoprazole sulfone can significantly stimulates gastric acid secretion by inhibiting H+, K+-ATPase. Lansoprazole sulfone has potential applications in duodenal ulcer, gastric ulcer, gastroesophageal reflux disease and Zolinger Ellison disease.
    Lansoprazole sulfone (Standard)
  • HY-W008794R
    Normetanephrine hydrochloride (Standard) 1011-74-1
    Normetanephrine (hydrochloride) (Standard) is the analytical standard of Normetanephrine (hydrochloride). This product is intended for research and analytical applications. Normetanephrine ((±)-Normetanephrine) hydrochloride is the O-methylated metabolite of norepinephrine (NE).
    Normetanephrine hydrochloride (Standard)
  • HY-W008807S
    Phosphoenolpyruvic acid (potassium)-13C2 201996-39-6 98%
    Phosphoenolpyruvic acid (potassium)-13C2 is the 13C labeled Phosphoenolpyruvic acid potassium (HY-W008807). Phosphoenolpyruvic acid (Phosphoenolpyruvate) potassium is a glycolysis metabolite with a high-energy phosphate group. Phosphoenolpyruvic acid potassium is involved in glycolysis and gluconeogenesis, and used as energy source to produce ATP, under the energy-limited conditions. Phosphoenolpyruvic acid potassium also exhibits cytoprotective and anti-oxidative properties.
    Phosphoenolpyruvic acid (potassium)-13C2
  • HY-W008940R
    Cytidine 5'-diphosphate disodium salt (Standard) 54394-90-0
    Cytidine 5'-diphosphate (disodium salt) (Standard) is the analytical standard of Cytidine 5'-diphosphate (disodium salt). This product is intended for research and analytical applications. Cytidine 5'-diphosphate (Cytidine) disodium salt is a nucleoside diphosphate that acts as a carrier for phosphorylcholine, diacylglycerol, and other molecules during phospholipid synthesis.
    Cytidine 5'-diphosphate disodium salt (Standard)
  • HY-W009081R
    Tricosanoic acid (Standard) 2433-96-7
    Naringenin (Standard) is the analytical standard of Naringenin. This product is intended for research and analytical applications. Naringenin is the predominant flavanone in Citrus reticulata Blanco; displays strong anti-inflammatory and antioxidant activities. Naringenin has anti-dengue virus (DENV) activity.
    Tricosanoic acid (Standard)
  • HY-W009162S
    Cytidine 5′-monophosphate-15N3 disodium 98%
    Cytidine 5′-monophosphate-15N3 (disodium) is the 15N labeled Cytidine 5'-monophosphate disodium. Cytidine 5'-monophosphate (5'-Cytidylic acid) disodium is a nucleotide which is used as a monomer in RNA. Cytidine 5'-monophosphate disodium consists of the nucleobase cytosine, the pentose sugar ribose, and the phosphate group.
    Cytidine 5′-monophosphate-15N3 disodium
Cat. No. Product Name / Synonyms Application Reactivity